SOMATULINE DEPOT HELPS LOWER CERTAIN HORMONES RELATED TO ACROMEGALY
What is Somatuline Depot?
Somatuline Depot is a type of medication called a somatostatin analog, or SSA. After surgery and/or radiation, SSAs are a medication doctors use to treat acromegaly. Somatuline Depot is thought to work by reducing the growth hormone (GH) production in your body. When there is less GH in your body, your liver produces less insulin-like growth factor 1 (IGF-1).
Starting treatment: What to expect
Once you begin treatment with Somatuline Depot, you may not see or feel any immediate changes. Remember, Somatuline Depot works by lowering the hormone levels in your body, so you might not know if it is working.
How did Somatuline Depot perform in clinical trials?
In studies of patients with acromegaly for whom surgery or radiotherapy did not work well enough or was not an option, Somatuline Depot lowered levels of GH and IGF-1. Your doctor may adjust your dosing or the time between injections based on your response to treatment.
Your doctor can adjust your dose of Somatuline Depot based on your response
Once you are controlled on your starting dose of 90 mg every 4 weeks for 3 months, the dose may then be adjusted, depending on your GH and IGF-1 levels and symptoms. If you are controlled* on 90 mg once every 4 weeks, then you may be considered for an extended dosing interval of Somatuline Depot 120 mg once every 6 or 8 weeks. By changing the dosing interval to once every 6 or 8 weeks, less frequent injections would be needed over the year. Your doctor will continue to monitor your response and adjust the dose as needed.
Controlled patients may have the opportunity to have fewer injections a year
*Controlled is defined as GH level from >1.0 ng/mL to ≤2.5 ng/mL, normalized IGF-1 level, and satisfactory management of clinical symptoms as determined by the healthcare provider.
How Somatuline Depot is administered
Somatuline Depot should be administered by a healthcare professional every 4 weeks.
Somatuline Depot comes in a sterile, prefilled syringe. It is injected deep under the skin of the upper outer area of your buttock.
- Your injection site should change (alternate) between your right and left buttock from one injection of Somatuline Depot to the next.
- During your treatment, your healthcare professional may do certain blood tests to see if Somatuline Depot is working.
In addition, Safe 'n' Sound ™ syringe technology provides
- Prefilled, low-volume syringe, which helps support full delivery of your dose
- Transparent design
- Retractable needle that engages automatically
- Manufacturing process using no latex or natural dry rubber
- Reinforced plunger design
Options of how to get your injections
In the doctor’s office
At home, via Home Health Administration, arranged through the IPSEN CARES® program; the cost is covered by Ipsen for eligible patients